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Clinical scale rapid expansion of lymphocytes for adoptive cell transfer therapy in the WAVE(® )bioreactor

BACKGROUND: To simplify clinical scale lymphocyte expansions, we investigated the use of the WAVE(®), a closed system bioreactor that utilizes active perfusion to generate high cell numbers in minimal volumes. METHODS: We have developed an optimized rapid expansion protocol for the WAVE bioreactor t...

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Detalles Bibliográficos
Autores principales:	Somerville, Robert PT, Devillier, Laura, Parkhurst, Maria R, Rosenberg, Steven A, Dudley, Mark E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402993/ https://www.ncbi.nlm.nih.gov/pubmed/22475724 http://dx.doi.org/10.1186/1479-5876-10-69

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