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Synaptic Plasticity and Learning in Animal Models of Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is caused by a mutation of either the Tsc1 or Tsc2 gene. As these genes work in concert to negatively regulate the mammalian target of rapamycin (mTOR) kinase which is involved in protein translation, mutations of these genes lead to a disinhibited mTOR activity. Bot...

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Detalles Bibliográficos
Autor principal: Kirschstein, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403083/
https://www.ncbi.nlm.nih.gov/pubmed/22848848
http://dx.doi.org/10.1155/2012/279834