Cargando…

Lung endothelial ADAM17 regulates the acute inflammatory response to lipopolysaccharide

Acute lung injury (ALI) is associated with increased vascular permeability, leukocyte recruitment, and pro-inflammatory mediator release. We investigated the role of the metalloproteinase ADAM17 in endotoxin-induced ALI with focus on endothelial ADAM17. In vitro, endotoxin-mediated induction of endo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dreymueller, Daniela, Martin, Christian, Kogel, Tanja, Pruessmeyer, Jessica, Hess, Franz M, Horiuchi, Keisuke, Uhlig, Stefan, Ludwig, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403298/ https://www.ncbi.nlm.nih.gov/pubmed/22367719 http://dx.doi.org/10.1002/emmm.201200217

Ejemplares similares

Shear Stress Counteracts Endothelial CX3CL1 Induction and Monocytic Cell Adhesion
por: Babendreyer, Aaron, et al.
Publicado: (2017)

Differential Induction of the ADAM17 Regulators iRhom1 and 2 in Endothelial Cells
por: Babendreyer, Aaron, et al.
Publicado: (2020)

Leukocyte ADAM17 Regulates Acute Pulmonary Inflammation
por: Arndt, Patrick G., et al.
Publicado: (2011)

ADAM12 and ADAM17 are essential molecules for hypoxia-induced impairment of neural vascular barrier function
por: Cui, Dan, et al.
Publicado: (2015)

A cytoplasmic C-terminal fragment of syndecan-1 is generated by sequential proteolysis and antagonizes syndecan-1 dependent lung tumor cell migration
por: Pasqualon, Tobias, et al.
Publicado: (2015)

Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis
por: Bolik, Julia, et al.
Publicado: (2021)

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
por: Kuhn, Peer-Hendrik, et al.
Publicado: (2016)

Multi-Antigen Imaging Reveals Inflammatory DC, ADAM17 and Neprilysin as Effectors in Keloid Formation
por: Rath, Mathias, et al.
Publicado: (2021)

Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP
por: Sammel, Martin, et al.
Publicado: (2019)

ADAM17-Mediated Shedding of Inflammatory Cytokines in Hypertension
por: de Queiroz, Thyago M., et al.
Publicado: (2020)

ADAM17 Deletion in Thymic Epithelial Cells Alters Aire Expression without Affecting T Cell Developmental Progression
por: Gravano, David M., et al.
Publicado: (2010)

The collectrin‐like part of the SARS‐CoV‐1 and ‐2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17
por: Niehues, Rabea Victoria, et al.
Publicado: (2022)

ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells
por: Mężyk-Kopeć, Renata, et al.
Publicado: (2015)

ADAM 17 endopeptidase
Publicado: (2009)

Upregulation of APP, ADAM10 and ADAM17 in the Denervated Mouse Dentate Gyrus
por: Del Turco, Domenico, et al.
Publicado: (2014)

Ectodomain Shedding by ADAM17 Increases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions
por: Klersy, Anton, et al.
Publicado: (2023)

Role of ADAM10 and ADAM17 in the Regulation of Keratinocyte Adhesion in Pemphigus Vulgaris
por: Kugelmann, Daniela, et al.
Publicado: (2022)

The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner
por: Seifert, Anke, et al.
Publicado: (2020)

ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages
por: Jiang, Yan, et al.
Publicado: (2022)

Role of Endothelial ADAM17 in Early Vascular Changes Associated with Diabetic Retinopathy
por: Shalaby, Lamiaa, et al.
Publicado: (2020)

ADAM10 and ADAM17: New Players in Trastuzumab Resistance
por: Duffy, Michael J., et al.
Publicado: (2014)

ADAM10 and ADAM17—Novel Players in Retinoblastoma Carcinogenesis
por: Van Meenen, Dario, et al.
Publicado: (2022)

Phosphatidylserine exposure is required for ADAM17 sheddase function
por: Sommer, Anselm, et al.
Publicado: (2016)

The perioperative time course and clinical significance of the chemokine CXCL16 in patients undergoing cardiac surgery
por: Dreymueller, Daniela, et al.
Publicado: (2015)

Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 1
por: Imoto, Issei, et al.
Publicado: (2021)

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation
por: Franzke, Claus-Werner, et al.
Publicado: (2012)

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation
por: Franzke, Claus-Werner, et al.
Publicado: (2012)

The role of ADAM17 in the T-cell response against bacterial pathogens
por: Link, Moritz Andreas, et al.
Publicado: (2017)

Role of ADAM10 and ADAM17 in Regulating CD137 Function
por: Seidel, Jana, et al.
Publicado: (2021)

Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17
por: Riethmueller, Steffen, et al.
Publicado: (2016)

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis
por: Fuchslocher Chico, Johaiber, et al.
Publicado: (2018)

ADAM17: An Emerging Therapeutic Target for Lung Cancer
por: Saad, Mohamed I., et al.
Publicado: (2019)

LRP1 shedding in human brain: roles of ADAM10 and ADAM17
por: Liu, Qiang, et al.
Publicado: (2009)

Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function
por: Leitzke, Sinje, et al.
Publicado: (2022)

Inactivation of Endothelial ADAM17 Reduces Retinal Ischemia-Reperfusion Induced Neuronal and Vascular Damage
por: Gutsaeva, Diana R, et al.
Publicado: (2020)

Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy
por: Palau, Vanesa, et al.
Publicado: (2021)

Endothelial ADAM17 Expression in the Progression of Kidney Injury in an Obese Mouse Model of Pre-Diabetes
por: Palau, Vanesa, et al.
Publicado: (2021)

The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release
por: Düsterhöft, Stefan, et al.
Publicado: (2021)

Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids
por: Matthews, Alexandra L., et al.
Publicado: (2017)

Blockade of the protease ADAM17 ameliorates experimental pancreatitis
por: Saad, Mohamed I., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vcmeuttuf1rqr7fl82qjda4n63