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The role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnover
The function of cytoplasmic PABPs [poly(A)-binding proteins] in promoting mRNA translation has been intensively studied. However, PABPs also have less clearly defined functions in mRNA turnover including roles in default deadenylation, a major rate-limiting step in mRNA decay, as well as roles in th...
Autores principales: | Brook, Matthew, Gray, Nicola K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403503/ https://www.ncbi.nlm.nih.gov/pubmed/22817748 http://dx.doi.org/10.1042/BST20120100 |
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