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Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors

BACKGROUND: Linaclotide has been proposed as a treatment for the same gastrointestinal indications for which lubiprostone has been approved, chronic idiopathic constipation and irritable bowel syndrome with constipation. Stressors damage the epithelial cell barrier and cellular homeostasis leading t...

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Detalles Bibliográficos
Autores principales:	Cuppoletti, John, Blikslager, Anthony T, Chakrabarti, Jayati, Nighot, Prashant K, Malinowska, Danuta H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403872/ https://www.ncbi.nlm.nih.gov/pubmed/22553939 http://dx.doi.org/10.1186/1471-2210-12-3

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