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Deprivation of arginine by recombinant human arginase in prostate cancer cells

BACKGROUND: Recombinant human arginase (rhArg) has been developed for arginine deprivation therapy in cancer, and is currently under clinical investigation. During pre-clinical evaluation, rhArg has exhibited significant anti-proliferative activity in cancer cells deficient in the expression of orni...

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Detalles Bibliográficos
Autores principales:	Hsueh, Eddy C, Knebel, Stephanie M, Lo, Wai-Hung, Leung, Yun-Chung, Cheng, Paul Ning-Man, Hsueh, Chung-Tsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403903/ https://www.ncbi.nlm.nih.gov/pubmed/22546217 http://dx.doi.org/10.1186/1756-8722-5-17

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