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Variability in detection and quantification of interferon β-1b–induced neutralizing antibodies

BACKGROUND: Interferon-beta (IFNB) therapy for multiple sclerosis can lead to the induction of neutralizing antibodies (NAbs) against IFNB. Various methods are used for detection and quantification of NAbs. METHODS: Blood samples from 125 IFNB-1b–treated patients, which were tested NAb negative or N...

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Detalles Bibliográficos
Autores principales:	Hartung, Hans-Peter, Kieseier, Bernd, Goodin, Douglas S, Arnason, Barry GW, Comi, Giancarlo, Cook, Stuart, Filippi, Massimo, Jeffery, Douglas R, Kappos, Ludwig, Bogumil, Timon, Stemper, Brigitte, Sandbrink, Rupert, Nakada, Yukiko, Nakajima, Haruhiko, Schwenke, Susanne, Lehr, Stephan, Heubach, Jürgen, Pohl, Christoph, Reischl, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403940/ https://www.ncbi.nlm.nih.gov/pubmed/22703536 http://dx.doi.org/10.1186/1742-2094-9-129

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