Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report

A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin dise...

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Autores principales: Karunarathne, Suneth, Weerasinghe, Sajitha, Govindapala, Dumitha, Fernando, Harshini, Jayaratne, Bhaddika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403954/
https://www.ncbi.nlm.nih.gov/pubmed/22513360
http://dx.doi.org/10.1186/1477-9560-10-4
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author Karunarathne, Suneth
Weerasinghe, Sajitha
Govindapala, Dumitha
Fernando, Harshini
Jayaratne, Bhaddika
author_facet Karunarathne, Suneth
Weerasinghe, Sajitha
Govindapala, Dumitha
Fernando, Harshini
Jayaratne, Bhaddika
author_sort Karunarathne, Suneth
collection PubMed
description A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly supportive.
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spelling pubmed-34039542012-07-25 Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report Karunarathne, Suneth Weerasinghe, Sajitha Govindapala, Dumitha Fernando, Harshini Jayaratne, Bhaddika Thromb J Case Report A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is commonly associated with cold agglutinin disease, gangrene is a rare complication. Management of secondary cold agglutinin disease is mainly supportive. BioMed Central 2012-04-18 /pmc/articles/PMC3403954/ /pubmed/22513360 http://dx.doi.org/10.1186/1477-9560-10-4 Text en Copyright ©2012 Karunarathne et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Karunarathne, Suneth
Weerasinghe, Sajitha
Govindapala, Dumitha
Fernando, Harshini
Jayaratne, Bhaddika
Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
title Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
title_full Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
title_fullStr Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
title_full_unstemmed Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
title_short Cold autoimmune haemolytic anaemia secondary to Epstein Barr virus infection presenting with peripheral gangrene; case report
title_sort cold autoimmune haemolytic anaemia secondary to epstein barr virus infection presenting with peripheral gangrene; case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403954/
https://www.ncbi.nlm.nih.gov/pubmed/22513360
http://dx.doi.org/10.1186/1477-9560-10-4
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