Cargando…

An olfactory ‘stress test’ may detect preclinical Alzheimer’s disease

BACKGROUND: The olfactory bulb (OB) receives extensive cholinergic input from the basal forebrain and is affected very early in Alzheimer’s disease (AD). We speculated that an olfactory ‘stress test’ (OST), targeting the OB, might be used to unmask incipient AD. We investigated if change in olfactor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schofield, Peter W, Ebrahimi, Houman, Jones, Alison L, Bateman, Grant A, Murray, Sonya R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403955/ https://www.ncbi.nlm.nih.gov/pubmed/22551361 http://dx.doi.org/10.1186/1471-2377-12-24

Ejemplares similares

Polygenic resilience score may be sensitive to preclinical Alzheimer’s disease changes
por: Eissman, Jaclyn M., et al.
Publicado: (2023)

Monthly At-Home Computerized Cognitive Testing to Detect Diminished Practice Effects in Preclinical Alzheimer's Disease
por: Jutten, Roos J., et al.
Publicado: (2022)

Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer’s disease
por: Müller, Stephan, et al.
Publicado: (2017)

Olfactory dysfunction in Alzheimer’s disease
por: Zou, Yong-ming, et al.
Publicado: (2016)

Unsupervised mobile cognitive testing for use in preclinical Alzheimer's disease
por: Papp, Kathryn V., et al.
Publicado: (2021)

Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease
por: Pichet Binette, Alexa, et al.
Publicado: (2021)

The unfolded protein response is activated in the olfactory system in Alzheimer’s disease
por: Murray, Helen C., et al.
Publicado: (2020)

MRI-based Alzheimer’s disease-resemblance atrophy index in the detection of preclinical and prodromal Alzheimer’s disease
por: Liu, Wanting, et al.
Publicado: (2021)

Preclinical Alzheimer's disease and longitudinal driving decline
por: Roe, Catherine M., et al.
Publicado: (2016)

Moving beyond disclosure: Stages of care in preclinical Alzheimer's disease biomarker testing
por: Ketchum, Fred B., et al.
Publicado: (2022)

Olfactory and Imaging Features in Atypical Alzheimer’s Disease
por: Huihong, Zhang, et al.
Publicado: (2018)

Olfactory Evaluation in Alzheimer’s Disease Model Mice
por: Zhang, Jingjing, et al.
Publicado: (2022)

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease
por: Lachen-Montes, Mercedes, et al.
Publicado: (2019)

Olfactory identification disorders due to Alzheimer’s disease: A new test from France to Quebec
por: Payne, Magali, et al.
Publicado: (2022)

Methodological Considerations in Canine Olfactory Detection Research
por: Lazarowski, Lucia, et al.
Publicado: (2020)

An Algorithm for Preclinical Diagnosis of Alzheimer's Disease
por: Khan, Tapan K.
Publicado: (2018)

Brain amyloid in preclinical Alzheimer's disease is associated with increased driving risk
por: Ott, Brian R., et al.
Publicado: (2016)

The Alzheimer’s Prevention Initiative Composite Cognitive Test: a practical measure for tracking cognitive decline in preclinical Alzheimer’s disease
por: Langbaum, Jessica B., et al.
Publicado: (2020)

Visuomotor integration deficits are common to familial and sporadic preclinical Alzheimer’s disease
por: Lu, Kirsty, et al.
Publicado: (2021)

Is pathological aging a successful resistance against amyloid-beta or preclinical Alzheimer’s disease?
por: Murray, Melissa E, et al.
Publicado: (2014)

A preclinical perspective on the enhanced vulnerability to Alzheimer's disease after early-life stress
por: Hoeijmakers, Lianne, et al.
Publicado: (2018)

Brief Test of Olfactory Dysfunction Based on Diagnostic Features of Specific Odors in Early-Stage Alzheimer Disease
por: Audronyte, Egle, et al.
Publicado: (2023)

Nonvascular retinal imaging markers of preclinical Alzheimer's disease
por: Snyder, Peter J., et al.
Publicado: (2016)

Validation of Olfactory Questionnaire in Koreans: an Alternative for Conventional Psychophysical Olfactory Tests
por: Kim, Jeong-Whun, et al.
Publicado: (2021)

Disruptions of the olfactory and default mode networks in Alzheimer's disease
por: Lu, Jiaming, et al.
Publicado: (2019)

Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer’s Disease Patients
por: Lampinen, Riikka, et al.
Publicado: (2022)

Olfactory memory in mild cognitive impairment and Alzheimer’s disease
por: Audronyte, Egle, et al.
Publicado: (2023)

Promising developments in neuropsychological approaches for the detection of preclinical Alzheimer’s disease: a selective review
por: Rentz, Dorene M, et al.
Publicado: (2013)

Sleep and Tau Pathology in Vietnam War Veterans with Preclinical and Prodromal Alzheimer’s Disease
por: Andrews, Murray, et al.
Publicado: (2021)

Mitochondrial SOS: how mtDNA may act as a stress signal in Alzheimer’s disease
por: Gorham, Isabelle K., et al.
Publicado: (2023)

Modelling of the dilated sagittal sinuses found in multiple sclerosis suggests increased wall stiffness may be a contributing factor
por: Bateman, Grant Alexander, et al.
Publicado: (2022)

Preclinical tests in Brazil
por: Taricano, Ingrid
Publicado: (2014)

Lamina-specific immunohistochemical signatures in the olfactory bulb of healthy, Alzheimer’s and Parkinson’s disease patients
por: Murray, Helen C., et al.
Publicado: (2022)

Preclinical diagnosis of Alzheimer’s disease: Prevention or prediction?
por: Nitrini, Ricardo
Publicado: (2010)

Entorhinal and Transentorhinal Atrophy in Preclinical Alzheimer's Disease
por: Kulason, Sue, et al.
Publicado: (2020)

Retinal layer thickness in preclinical Alzheimer's disease
por: van de Kreeke, Jacoba A., et al.
Publicado: (2019)

Onset of Preclinical Alzheimer Disease in Monozygotic Twins
por: Konijnenberg, Elles, et al.
Publicado: (2021)

Gut microbiome alterations in preclinical Alzheimer’s disease
por: Jung, Joon Hyung, et al.
Publicado: (2022)

Precipitating Mechanisms of Falls in Preclinical Alzheimer’s Disease
por: Keleman, Audrey A., et al.
Publicado: (2023)

Spanish Validation for Olfactory Function Testing Using the Sniffin’ Sticks Olfactory Test: Threshold, Discrimination, and Identification
por: Delgado-Losada, María Luisa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d1nkod6es1plpkgn2huimq042n