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Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells

BACKGROUND: Pirfenidone is a novel anti-fibrotic and anti-inflammatory agent that inhibits the progression of fibrosis in animal models and in patients with idiopathic pulmonary fibrosis (IPF). We previously showed that pirfenidone inhibits the over-expression of collagen type I and of heat shock pr...

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Detalles Bibliográficos
Autores principales:	Hisatomi, Keiko, Mukae, Hiroshi, Sakamoto, Noriho, Ishimatsu, Yuji, Kakugawa, Tomoyuki, Hara, Shintaro, Fujita, Hanako, Nakamichi, Seiko, Oku, Hisashi, Urata, Yoshishige, Kubota, Hiroshi, Nagata, Kazuhiro, Kohno, Shigeru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403980/ https://www.ncbi.nlm.nih.gov/pubmed/22694981 http://dx.doi.org/10.1186/1471-2466-12-24

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