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Aldolase B Knockdown Prevents High Glucose-Induced Methylglyoxal Overproduction and Cellular Dysfunction in Endothelial Cells

We used cultured endothelial cells as a model to examine whether up-regulation of aldolase B and enhanced methylglyoxal (MG) formation play an important role in high glucose-induced overproduction of advanced glycosylation endproducts (AGEs), oxidative stress and cellular dysfunction. High glucose (...

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Detalles Bibliográficos
Autores principales:	Liu, Jianghai, Mak, Timothy Chun-Ping, Banigesh, Ali, Desai, Kaushik, Wang, Rui, Wu, Lingyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404030/ https://www.ncbi.nlm.nih.gov/pubmed/22911800 http://dx.doi.org/10.1371/journal.pone.0041495

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