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Fra-1/AP-1 Transcription Factor Negatively Regulates Pulmonary Fibrosis In Vivo
The Fra-1/AP-1 transcription factor plays a key role in tumor epithelial cell progression; however, its role in pathogenic lung fibrosis remains unclear. In the present study, using a genetic approach (Fra-1 deficient mice), we have demonstrated a novel regulatory (protective) role for Fra-1 in lung...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404039/ https://www.ncbi.nlm.nih.gov/pubmed/22911824 http://dx.doi.org/10.1371/journal.pone.0041611 |