Cargando…

Salvinorin A Administration after Global Cerebral Hypoxia/Ischemia Preserves Cerebrovascular Autoregulation via Kappa Opioid Receptor in Piglets

BACKGROUND: Cerebral hypoxia/ischemia (HI) is not uncommon during the perinatal period. If occurring, it can result in severe neurologic disabilities that persist throughout life. Salvinorin A, a non-opioid Kappa opioid receptors (KOR) selective agonist, has the potential to address this devastating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhenhong, Ma, Nan, Riley, John, Armstead, William M., Liu, Renyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404042/ https://www.ncbi.nlm.nih.gov/pubmed/22911847 http://dx.doi.org/10.1371/journal.pone.0041724

Ejemplares similares

Kappa Opioids, Salvinorin A and Major Depressive Disorder
por: Taylor, George T., et al.
Publicado: (2016)

Salvinorin A preserves cerebral pial artery autoregulation after forebrain ischemia via the PI3K/AKT/cGMP pathway
por: Dong, H.P., et al.
Publicado: (2018)

The Kappa Opioid Receptor and the Sleep of Reason: Cortico-Subcortical Imbalance Following Salvinorin-A
por: Ona, Genís, et al.
Publicado: (2021)

Solving an Old Puzzle: Elucidation and Evaluation of the Binding Mode of Salvinorin A at the Kappa Opioid Receptor
por: Puls, Kristina, et al.
Publicado: (2023)

Salvinorin A decreases mortality and improves neurological outcome in a neonatal mouse hypoxia model
por: Chen, Chunhua, et al.
Publicado: (2014)

Lack of effect of sublingual salvinorin A, a naturally occurring kappa opioid, in humans: a placebo-controlled trial
por: Mendelson, John E., et al.
Publicado: (2010)

Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders
por: Butelman, Eduardo R., et al.
Publicado: (2015)

Synthesis and κ-Opioid Receptor Activity of Furan-Substituted Salvinorin A Analogues
por: Riley, Andrew P., et al.
Publicado: (2014)

Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders
por: Cichon, Joseph, et al.
Publicado: (2022)

Corrigendum: Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders
por: Butelman, Eduardo R., et al.
Publicado: (2015)

Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents
por: Kivell, Bronwyn M., et al.
Publicado: (2018)

Investigation of Cerebral Autoregulation in the Newborn Piglet During Anaesthesia and Surgery
por: Bale, Gemma, et al.
Publicado: (2014)

8-epi-Salvinorin B: crystal structure and affinity at the κ opioid receptor
por: Munro, Thomas A, et al.
Publicado: (2007)

Kappa Opioid Receptor on Pulmonary Macrophages and Immune Function
por: Zeng, Si, et al.
Publicado: (2020)

Impaired Dynamic Cerebral Autoregulation and Cerebrovascular Reactivity in Middle Cerebral Artery Stenosis
por: Chen, Jie, et al.
Publicado: (2014)

The Salvinorin Analogue, Ethoxymethyl Ether Salvinorin B, Promotes Remyelination in Preclinical Models of Multiple Sclerosis
por: Paton, Kelly F., et al.
Publicado: (2021)

Salvinorin A: A Mini Review of Physical and Chemical Properties Affecting Its Translation from Research to Clinical Applications in Humans
por: Orton, Edward, et al.
Publicado: (2014)

Major Depressive Disorder and Kappa Opioid Receptor Antagonists
por: Li, Wei, et al.
Publicado: (2016)

Modelling Cerebrovascular Reactivity: A Novel Near-Infrared Biomarker of Cerebral Autoregulation?
por: Highton, David, et al.
Publicado: (2012)

Conductivity reactivity index for monitoring of cerebrovascular autoregulation in early cerebral ischemic rabbits
por: Xu, Jia, et al.
Publicado: (2023)

Early Cerebrovascular Autoregulation in Neonates with Congenital Heart Disease
por: Brunsch, Celina L., et al.
Publicado: (2022)

Formal Total Synthesis of Salvinorin A
por: Halang, Marc, et al.
Publicado: (2022)

Dopamine therapy does not affect cerebral autoregulation during hypotension in newborn piglets
por: Eriksen, Vibeke Ramsgaard, et al.
Publicado: (2017)

The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors
por: van de Wetering, Ross, et al.
Publicado: (2023)

Cutting-Edge Search for Safer Opioid Pain Relief: Retrospective Review of Salvinorin A and Its Analogs
por: Zjawiony, Jordan K., et al.
Publicado: (2019)

Influence of CO(2) on neurovascular coupling: interaction with dynamic cerebral autoregulation and cerebrovascular reactivity
por: Maggio, Paola, et al.
Publicado: (2014)

Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy
por: Howlett, Jessica A., et al.
Publicado: (2013)

Salvinorin B methoxymethyl ether
por: Munro, Thomas A., et al.
Publicado: (2012)

Studies toward bivalent κ opioids derived from salvinorin A: heteromethylation of the furan ring reduces affinity
por: Munro, Thomas A, et al.
Publicado: (2013)

Cerebrovascular reactivity and cerebral autoregulation are improved in the supine posture compared to upright in healthy men and women
por: Favre, Michelle E., et al.
Publicado: (2020)

Repeated Administration of Norbinaltorphimine Produces Cumulative Kappa Opioid Receptor Inactivation
por: Chavkin, Charles, et al.
Publicado: (2019)

Impaired cerebrovascular autoregulation in patients with severe sepsis and sepsis-associated delirium
por: Schramm, Patrick, et al.
Publicado: (2012)

δ-Opioid Receptors, microRNAs, and Neuroinflammation in Cerebral Ischemia/Hypoxia
por: Chen, Yi-Meng, et al.
Publicado: (2020)

Unusual hemiacetal structure derived from Salvinorin A
por: Carvalho, Paulo, et al.
Publicado: (2008)

Salvinorin A Does Not Affect Seizure Threshold in Mice
por: Socała, Katarzyna, et al.
Publicado: (2020)

A Protecting‐Group‐Free Synthesis of (−)‐Salvinorin A
por: Zimdars, Patrick, et al.
Publicado: (2021)

No Differences in Cerebral Immunohistochemical Markers following Remote Ischemic Postconditioning in Newborn Piglets with Hypoxia–Ischemia
por: Andersen, Hannah B., et al.
Publicado: (2022)

Sex And Age Differences In Phenylephrine Mechanisms And Outcomes After Piglet Brain Injury
por: Curvello, Victor, et al.
Publicado: (2017)

Autoregulation assessment by direct visualisation of pial arterial blood flow in the piglet brain
por: Klein, S. P., et al.
Publicado: (2019)

Delayed Toxic-Hypoxic Leukoencephalopathy As Sequela of Opioid Overdose and Cerebral Hypoxia-Ischemia
por: Chachkhiani, David, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kg0ck8pvde8b43c1nhdj7cj4dj