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No Influence of Dabigatran Anticoagulation on Hemorrhagic Transformation in an Experimental Model of Ischemic Stroke

BACKGROUND: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after experimental stroke under DE treatment as we...

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Detalles Bibliográficos
Autores principales: Bohmann, Ferdinand, Mirceska, Ana, Pfeilschifter, Josef, Lindhoff-Last, Edelgard, Steinmetz, Helmuth, Foerch, Christian, Pfeilschifter, Waltraud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404053/
https://www.ncbi.nlm.nih.gov/pubmed/22911709
http://dx.doi.org/10.1371/journal.pone.0040804