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Mycobacterium tuberculosis Infection of Dendritic Cells Leads to Partially Caspase-1/11-Independent IL-1β and IL-18 Secretion but Not to Pyroptosis

BACKGROUND: Interleukin-1β (IL-1β) is important for host resistance against Mycobacterium tuberculosis (Mtb) infections. The response of the dendritic cell inflammasome during Mtb infections has not been investigated in detail. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that Mtb infection of bone...

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Detalles Bibliográficos
Autores principales:	Abdalla, Hana, Srinivasan, Lalitha, Shah, Swati, Mayer-Barber, Katrin D., Sher, Alan, Sutterwala, Fayyaz S., Briken, Volker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404059/ https://www.ncbi.nlm.nih.gov/pubmed/22911706 http://dx.doi.org/10.1371/journal.pone.0040722

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