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A Multi-Factorial Genetic Model for Prognostic Assessment of High Risk Melanoma Patients Receiving Adjuvant Interferon
PURPOSE: IFNa was the first cytokine to demonstrate anti-tumor activity in advanced melanoma. Despite the ability of high-dose IFNa reducing relapse and mortality by up to 33%, large majority of patients experience side effects and toxicity which outweigh the benefits. The current study attempts to...
Autores principales: | Wang, Ena, Zhao, Yingdong, Monaco, Alessandro, Uccellini, Lorenzo, Kirkwood, John M., Spyropoulou-Vlachou, Maria, Panelli, Monica C., Marincola, Francesco M., Gogas, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404079/ https://www.ncbi.nlm.nih.gov/pubmed/22911710 http://dx.doi.org/10.1371/journal.pone.0040805 |
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