Cargando…

Serotonin Transporter Gene (SLC6A4) Variations Are Associated with Poor Survival in Colorectal Cancer Patients

Prognosis in colorectal cancer patients is quite variable, even after adjustment for clinical parameters such as disease stage and microsatellite instability status. It is possible that the psychological distress experienced by patients, including anxiety and depression, may be correlated with poor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Savas, Sevtap, Hyde, Angela, Stuckless, Susan N., Parfrey, Patrick, Younghusband, H. Banfield, Green, Roger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404081/ https://www.ncbi.nlm.nih.gov/pubmed/22911682 http://dx.doi.org/10.1371/journal.pone.0038953

Ejemplares similares

MTHFR Glu429Ala and ERCC5 His46His Polymorphisms Are Associated with Prognosis in Colorectal Cancer Patients: Analysis of Two Independent Cohorts from Newfoundland
por: Negandhi, Amit A., et al.
Publicado: (2013)

Examining the Polymorphisms in the Hypoxia Pathway Genes in Relation to Outcome in Colorectal Cancer
por: Haja Mohideen, Asan M. S., et al.
Publicado: (2014)

No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients
por: Dan, Lydia A., et al.
Publicado: (2016)

A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer
por: Savas, Sevtap, et al.
Publicado: (2015)

A genome wide association study on Newfoundland colorectal cancer patients’ survival outcomes
por: Xu, Wei, et al.
Publicado: (2015)

Mitochondrial DNA polymorphisms, its copy number change and outcome in colorectal cancer
por: Haja Mohideen, Asan Meera Sahib, et al.
Publicado: (2015)

Two functional indel polymorphisms in the promoter region of the Brahma gene (BRM) and disease risk and progression-free survival in colorectal cancer
por: Yu, Yajun, et al.
Publicado: (2018)

The long-term survival characteristics of a cohort of colorectal cancer patients and baseline variables associated with survival outcomes with or without time-varying effects
por: Yu, Yajun, et al.
Publicado: (2019)

Variation and appropriateness of antipsychotic use in long-term care facilities across Newfoundland and Labrador
por: Giovannini-Green, Zachary E. M., et al.
Publicado: (2021)

A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer
por: Penney, Michelle E., et al.
Publicado: (2019)

Correction to: A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer
por: Penney, Michelle E., et al.
Publicado: (2019)

Associations of single nucleotide polymorphisms with mucinous colorectal cancer: genome-wide common variant and gene-based rare variant analyses
por: Penney, Michelle E., et al.
Publicado: (2018)

Dietary patterns and colorectal cancer recurrence and survival: a cohort study
por: Zhu, Yun, et al.
Publicado: (2013)

Germline INDELs and CNVs in a cohort of colorectal cancer patients: their characteristics, associations with relapse‐free survival time, and potential time‐varying effects on the risk of relapse
por: Werdyani, Salem, et al.
Publicado: (2017)

A comprehensive analysis of SNPs and CNVs identifies novel markers associated with disease outcomes in colorectal cancer
por: Yu, Yajun, et al.
Publicado: (2021)

Examining SNP-SNP interactions and risk of clinical outcomes in colorectal cancer using multifactor dimensionality reduction based methods
por: Curtis, Aaron, et al.
Publicado: (2022)

Multifactor dimensionality reduction method identifies novel SNP interactions in the WNT protein interaction networks that are associated with recurrence risk in colorectal cancer
por: Curtis, Aaron A., et al.
Publicado: (2023)

XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer
por: He, Yanjing, et al.
Publicado: (2018)

Vitamin D receptor and calcium-sensing receptor polymorphisms and colorectal cancer survival in the Newfoundland population
por: Zhu, Yun, et al.
Publicado: (2017)

Public Interest Group on Cancer Research: a successful patient–researcher partnership in Newfoundland and Labrador
por: Savas, Sevtap, et al.
Publicado: (2022)

Serotonin transporter gene (SLC6A4) variation and sensory processing sensitivity—Comparison with other anxiety‐related temperamental dimensions
por: Licht, Cecilie L., et al.
Publicado: (2020)

Serotonin Transporter Gene (SLC6A4) Polymorphism and Mucosal Serotonin Levels in Southeastern Iranian Patients with Irritable Bowel Syndrome
por: Mohammadi, Mojgan, et al.
Publicado: (2017)

Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake
por: Zhu, Yun, et al.
Publicado: (2018)

Epigenetic adaptation of the placental serotonin transporter gene (SLC6A4) to gestational diabetes mellitus
por: Blazevic, Sofia, et al.
Publicado: (2017)

Association Study of Serotonin Transporter SLC6A4 Gene with Chinese Han Irritable Bowel Syndrome
por: Yuan, Jing, et al.
Publicado: (2014)

Emotional Voice Processing: Investigating the Role of Genetic Variation in the Serotonin Transporter across Development
por: Grossmann, Tobias, et al.
Publicado: (2013)

Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age
por: Weikum, Whitney M., et al.
Publicado: (2013)

Study of the serotonin transporter (SLC6A4) and BDNF genes in French patients with non syndromic mental deficiency
por: Tabagh, Refaat, et al.
Publicado: (2010)

Elevated Expression of SLC6A4 Encoding the Serotonin Transporter (SERT) in Gilles de la Tourette Syndrome
por: Hildonen, Mathis, et al.
Publicado: (2021)

Serotonin and serotonin transporter levels in autistic children
por: Abdulamir, Haidar A., et al.
Publicado: (2018)

Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation
por: Green, Evan M., et al.
Publicado: (2015)

X-ray structures and mechanism of the human serotonin transporter
por: Coleman, Jonathan A., et al.
Publicado: (2016)

Cognitive impact of genetic variation of the serotonin transporter in primates is associated with differences in brain morphology rather than serotonin neurotransmission
por: Jedema, Hank P., et al.
Publicado: (2009)

Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
por: Lindholm Carlström, Eva, et al.
Publicado: (2012)

Genotype-dependent associations between serotonin transporter gene (SLC6A4) DNA methylation and late-life depression
por: Lam, Dilys, et al.
Publicado: (2018)

Association between resilience and a functional polymorphism in the serotonin transporter (SLC6A4) gene: A meta-analysis
por: González-Giraldo, Yeimy, et al.
Publicado: (2020)

Influence of pre-diagnostic cigarette smoking on colorectal cancer survival: overall and by tumour molecular phenotype
por: Zhu, Y, et al.
Publicado: (2014)

The serotonin transporter gene and female personality variation in a free-living passerine
por: Thys, Bert, et al.
Publicado: (2021)

SLC6 transporter oligomerization
por: Jayaraman, Kumaresan, et al.
Publicado: (2020)

Specific Variants in the MLH1 Gene Region May Drive DNA Methylation, Loss of Protein Expression, and MSI-H Colorectal Cancer
por: Mrkonjic, Miralem, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ektkv3hulecnvgenv1pjtba46j