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Vascular Disrupting Agent Drug Classes Differ in Effects on the Cytoskeleton

Vascular disrupting agents (VDAs), anti-cancer drugs that target established tumor blood vessels, fall into two main classes: microtubule targeting drugs, exemplified by combretastatin A4 (CA4), and flavonoids, exemplified by 5,6-dimethylxanthenone-4-acetic acid (DMXAA). Both classes increase permea...

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Detalles Bibliográficos
Autores principales:	Kim, Sujeong, Peshkin, Leonid, Mitchison, Timothy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404093/ https://www.ncbi.nlm.nih.gov/pubmed/22848372 http://dx.doi.org/10.1371/journal.pone.0040177

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