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Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Medicines against second stage HAT, where parasites have invaded the central nervous system (CNS). The...

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Detalles Bibliográficos
Autores principales:	Thuita, John K., Wang, Michael Z., Kagira, John M., Denton, Cathrine L., Paine, Mary F., Mdachi, Raymond E., Murilla, Grace A., Ching, Shelley, Boykin, David W., Tidwell, Richard R., Hall, James E., Brun, Reto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404106/ https://www.ncbi.nlm.nih.gov/pubmed/22848769 http://dx.doi.org/10.1371/journal.pntd.0001734

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