Cargando…
The Fas/CD95 Receptor Regulates the Death of Autoreactive B Cells and the Selection of Antigen-Specific B Cells
Cell death receptors have crucial roles in the regulation of immune responses. Here we review recent in vivo data confirming that the Fas death receptor (TNFSR6) on B cells is important for the regulation of autoimmunity since the impairment of only Fas function on B cells results in uncontrolled au...
Autores principales: | Koncz, Gabor, Hueber, Anne-Odile |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404404/ https://www.ncbi.nlm.nih.gov/pubmed/22848207 http://dx.doi.org/10.3389/fimmu.2012.00207 |
Ejemplares similares
-
N-Glycosylation Site Analysis of Citrullinated Antigen-Specific B-Cell Receptors Indicates Alternative Selection Pathways During Autoreactive B-Cell Development
por: Vergroesen, Rochelle D., et al.
Publicado: (2019) -
The Peripheral Deletion of Autoreactive CD8(+) T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)
por: Kurts, Christian, et al.
Publicado: (1998) -
CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases
por: Le Gallo, Matthieu, et al.
Publicado: (2017) -
Fas Versatile Signaling and Beyond: Pivotal Role of Tyrosine Phosphorylation in Context-Dependent Signaling and Diseases
por: Chakrabandhu, Krittalak, et al.
Publicado: (2016) -
Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation
por: Williams, Jesse W., et al.
Publicado: (2018)