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Tailoring subunit vaccine immunogenicity: Maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1()
Subunit vaccination modalities tend to induce particular immune effector responses. Viral vectors are well known for their ability to induce strong T cell responses, while protein-adjuvant vaccines have been used primarily for induction of antibody responses. Here, we demonstrate in mice using a Pla...
Autores principales: | Douglas, Alexander D., de Cassan, Simone C., Dicks, Matthew D.J., Gilbert, Sarah C., Hill, Adrian V.S., Draper, Simon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404461/ https://www.ncbi.nlm.nih.gov/pubmed/20937436 http://dx.doi.org/10.1016/j.vaccine.2010.08.068 |
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