Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model

AIMS: Remodelling of the extracellular matrix (ECM) plays an important role in the production of arrhythmogenic substrate for atrial fibrillation (AF), and is considered to be promoted by the connective tissue growth factor (CTGF). Our objective was to assess the relationship between CTGF and ECM sy...

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Autores principales: Kiryu, Michiro, Niwano, Shinichi, Niwano, Hiroe, Kishihara, Jun, Aoyama, Yuya, Fukaya, Hidehira, Masaki, Yoshihiko, Izumi, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404558/
https://www.ncbi.nlm.nih.gov/pubmed/22454409
http://dx.doi.org/10.1093/europace/eus052

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