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A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
Ubiquitination of histones plays a critical role in the regulation of several processes within the nucleus, including maintenance of genome stability and transcriptional regulation. The only known ubiquitination site on histones is represented by a conserved Lys residue located at the C terminus of...
Autores principales: | Gatti, Marco, Pinato, Sabrina, Maspero, Elena, Soffientini, Paolo, Polo, Simona, Penengo, Lorenza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404880/ https://www.ncbi.nlm.nih.gov/pubmed/22713238 http://dx.doi.org/10.4161/cc.20919 |
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