LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression

In the mitotic exit network of budding yeast, Dbf2 kinase phosphorylates and regulates Cdc14 phosphatase. In contrast, no phosphatase substrates of LATS1/WARTS kinase, the mammalian equivalent of Dbf2, has been reported. To address this discrepancy, we performed phosphoproteomic screening using LATS...

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Detalles Bibliográficos
Autores principales: Chiyoda, Tatsuyuki, Sugiyama, Naoyuki, Shimizu, Takatsune, Naoe, Hideaki, Kobayashi, Yusuke, Ishizawa, Jo, Arima, Yoshimi, Tsuda, Hiroshi, Ito, Masaaki, Kaibuchi, Kozo, Aoki, Daisuke, Ishihama, Yasushi, Saya, Hideyuki, Kuninaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404884/
https://www.ncbi.nlm.nih.gov/pubmed/22641346
http://dx.doi.org/10.1083/jcb.201110110

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