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Cysteinyl Leukotriene Signaling Aggravates Myocardial Hypoxia in Experimental Atherosclerotic Heart Disease

BACKGROUND: Cysteinyl-leukotrienes (cys-LT) are powerful spasmogenic and immune modulating lipid mediators involved in inflammatory diseases, in particular asthma. Here, we investigated whether cys-LT signaling, in the context of atherosclerotic heart disease, compromises the myocardial microcircula...

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Detalles Bibliográficos
Autores principales:	Nobili, Elena, Salvado, M. Dolores, Folkersen, Lasse, Castiglioni, Laura, Kastrup, Jens, Wetterholm, Anders, Tremoli, Elena, Hansson, Göran K., Sironi, Luigi, Haeggström, Jesper Z., Gabrielsen, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404957/ https://www.ncbi.nlm.nih.gov/pubmed/22848603 http://dx.doi.org/10.1371/journal.pone.0041786

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