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Long-Chain Acylcarnitines Regulate the hERG Channel

BACKGROUND AND PURPOSE: In some pathological conditions carnitine concentration is high while in othersitis low.In bothcases,cardiac arrhythmiascan occur and lead to sudden cardiac death. It has been proposed that in ischaemia, acylcarnitine (acyl-CAR), but not carnitine, is involved in arrhythmiast...

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Detalles Bibliográficos
Autores principales: Ferro, Fabio, Ouillé, Aude, Tran, Truong-An, Fontanaud, Pierre, Bois, Patrick, Babuty, Dominique, Labarthe, François, Le Guennec, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404973/
https://www.ncbi.nlm.nih.gov/pubmed/22848566
http://dx.doi.org/10.1371/journal.pone.0041686