The Obesity-Related Peptide Leptin Sensitizes Cardiac Mitochondria to Calcium-Induced Permeability Transition Pore Opening and Apoptosis

The obesity-related 16 kDa peptide leptin is synthesized primarily in white adipocytes although its production has been reported in other tissues including the heart. There is emerging evidence that leptin may contribute to cardiac pathology especially that related to myocardial remodelling and hear...

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Detalles Bibliográficos
Autores principales: Martinez-Abundis, Eduardo, Rajapurohitam, Venkatesh, Haist, James V., Gan, Xiaohong T., Karmazyn, Morris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405002/
https://www.ncbi.nlm.nih.gov/pubmed/22848545
http://dx.doi.org/10.1371/journal.pone.0041612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405002/
https://www.ncbi.nlm.nih.gov/pubmed/22848545
http://dx.doi.org/10.1371/journal.pone.0041612

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