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Induction of Heme Oxygenase-1 Inhibits Cell Death in Crotonaldehyde-Stimulated HepG2 Cells via the PKC-δ -p38 -Nrf2 Pathway
BACKGROUND: Crotonaldehyde, an alpha, beta-unsaturated aldehyde present in cigarette smoke, is an environmental pollutant and a product of lipid peroxidation. It also produces adverse effects to humans and is considered as a risk factor for various diseases. Heme oxygenase-1 (HO-1) plays important r...
Autores principales: | Lee, Seung Eun, Yang, Hana, Jeong, Seong Il, Jin, Young-Ho, Park, Cheung-Seog, Park, Yong Seek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405012/ https://www.ncbi.nlm.nih.gov/pubmed/22848562 http://dx.doi.org/10.1371/journal.pone.0041676 |
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