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A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity
The HIV vaccine strategy that, to date, generated immune protection consisted of a prime-boost regimen using a canarypox vector and an HIV envelope protein with alum, as shown in the RV144 trial. Since the efficacy was weak, and previous HIV vaccine trials designed to generate antibody responses fai...
Autores principales: | Pattacini, Laura, Mize, Gregory J., Graham, Jessica B., Fluharty, Tayler R., Graham, Tisha M., Lingnau, Karen, Wizel, Benjamin, Perdiguero, Beatriz, Esteban, Mariano, Pantaleo, Giuseppe, Shen, Mingchao, Spies, Gregory A., McElrath, M. Juliana, Lund, Jennifer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405041/ https://www.ncbi.nlm.nih.gov/pubmed/22848738 http://dx.doi.org/10.1371/journal.pone.0042163 |
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