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Fibroblast EXT1-Levels Influence Tumor Cell Proliferation and Migration in Composite Spheroids

BACKGROUND: Stromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan sulfate proteoglycans, present both on tumor and stromal cells, interact with a...

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Detalles Bibliográficos
Autores principales:	Österholm, Cecilia, Lu, Ning, Lidén, Åsa, Karlsen, Tine V., Gullberg, Donald, Reed, Rolf K., Kusche-Gullberg, Marion
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405129/ https://www.ncbi.nlm.nih.gov/pubmed/22848466 http://dx.doi.org/10.1371/journal.pone.0041334

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