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Contact Sensitizers Induce Skin Inflammation via ROS Production and Hyaluronic Acid Degradation
BACKGROUND: Allergic contact dermatitis (ACD) represents a severe health problem with increasing worldwide prevalence. It is a T cell-mediated skin disease induced by protein-reactive organic and inorganic chemicals. A key feature of contact allergens is their ability to trigger an innate immune res...
Autores principales: | Esser, Philipp R., Wölfle, Ute, Dürr, Christoph, von Loewenich, Friederike D., Schempp, Christoph M., Freudenberg, Marina A., Jakob, Thilo, Martin, Stefan F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405137/ https://www.ncbi.nlm.nih.gov/pubmed/22848468 http://dx.doi.org/10.1371/journal.pone.0041340 |
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