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Different cellular p16(INK4a) localisation may signal different survival outcomes in head and neck cancer

BACKGROUND: Recently, the management of head and neck squamous cell carcinoma (HNSCC) has focused considerable attention on biomarkers, which may influence outcomes. Tests for human papilloma infection, including direct assessment of the virus as well as an associated tumour suppressor gene p16, are...

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Detalles Bibliográficos
Autores principales: Zhao, N, Ang, M-K, Yin, X-Y, Patel, M R, Fritchie, K, Thorne, L, Muldrew, K L, Hayward, M C, Sun, W, Wilkerson, M D, Chera, B S, Hackman, T, Zanation, A M, Grilley-Olson, J E, Couch, M E, Shockley, W W, Weissler, M C, Shores, C G, Funkhouser, W K, Olshan, A F, Hayes, D N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405208/
https://www.ncbi.nlm.nih.gov/pubmed/22735904
http://dx.doi.org/10.1038/bjc.2012.264