Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes

ABSTRACT: N-Alkyltheobromine (1–9) derivatives were obtained by reacting theobromine with appropriate alkyl halide under microwave irradiation at 100–150 W and by conventional synthesis. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were considered. The pre...

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Autores principales: Skwierawska, A., Pazik, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405244/
https://www.ncbi.nlm.nih.gov/pubmed/22866022
http://dx.doi.org/10.1007/s10847-011-0093-5
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author Skwierawska, A.
Pazik, A.
author_facet Skwierawska, A.
Pazik, A.
author_sort Skwierawska, A.
collection PubMed
description ABSTRACT: N-Alkyltheobromine (1–9) derivatives were obtained by reacting theobromine with appropriate alkyl halide under microwave irradiation at 100–150 W and by conventional synthesis. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were considered. The presented compounds 1–5 have been studied as ion carriers in ion-selective membrane electrodes. Selectivity of these membranes was studied towards various anions in addition to transition and heavy metal cations. GRAPHICAL ABSTRACT: Alkylations of theobromine under microwave irradiation at 100–150 W and by conventional synthesis were performed. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were observed. The achieved compounds have been studied as ion carriers in ion-selective membrane electrodes. [Image: see text]
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spelling pubmed-34052442012-08-02 Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes Skwierawska, A. Pazik, A. J Incl Phenom Macrocycl Chem Original Article ABSTRACT: N-Alkyltheobromine (1–9) derivatives were obtained by reacting theobromine with appropriate alkyl halide under microwave irradiation at 100–150 W and by conventional synthesis. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were considered. The presented compounds 1–5 have been studied as ion carriers in ion-selective membrane electrodes. Selectivity of these membranes was studied towards various anions in addition to transition and heavy metal cations. GRAPHICAL ABSTRACT: Alkylations of theobromine under microwave irradiation at 100–150 W and by conventional synthesis were performed. Formation of by-products of oxygen atom alkylation and 1-N-alkyltheobromine ring opening were observed. The achieved compounds have been studied as ion carriers in ion-selective membrane electrodes. [Image: see text] Springer Netherlands 2011-12-11 2012 /pmc/articles/PMC3405244/ /pubmed/22866022 http://dx.doi.org/10.1007/s10847-011-0093-5 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Article
Skwierawska, A.
Pazik, A.
Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes
title Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes
title_full Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes
title_fullStr Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes
title_full_unstemmed Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes
title_short Inhibition of impurities formation in the synthesis of N-alkyltheobromines stimulated by microwave irradiation. Cationic and anionic response of membrane electrodes
title_sort inhibition of impurities formation in the synthesis of n-alkyltheobromines stimulated by microwave irradiation. cationic and anionic response of membrane electrodes
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405244/
https://www.ncbi.nlm.nih.gov/pubmed/22866022
http://dx.doi.org/10.1007/s10847-011-0093-5
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AT pazika inhibitionofimpuritiesformationinthesynthesisofnalkyltheobrominesstimulatedbymicrowaveirradiationcationicandanionicresponseofmembraneelectrodes

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