Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease

BACKGROUND: Neuroinflammation is associated with virtually all major neurodegenerative disorders, including Alzheimer’s disease (AD). Although it remains unclear whether neuroinflammation is the driving force behind these disorders, compelling evidence implicates its role in exacerbating disease pro...

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Detalles Bibliográficos
Autores principales: Tweedie, David, Ferguson, Ryan A, Fishman, Kelly, Frankola, Kathryn A, Van Praag, Henriette, Holloway, Harold W, Luo, Weiming, Li, Yazhou, Caracciolo, Luca, Russo, Isabella, Barlati, Sergio, Ray, Balmiki, Lahiri, Debomoy K, Greig, Nigel H, Rosi, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405480/
https://www.ncbi.nlm.nih.gov/pubmed/22642825
http://dx.doi.org/10.1186/1742-2094-9-106

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