Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening

Pseudomonas aeruginosa is a leading cause of hospital-associated infections in the seriously ill, and the primary agent of chronic lung infections in cystic fibrosis patients. A major obstacle to effective control of P. aeruginosa infections is its intrinsic resistance to most antibiotic classes, wh...

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Detalles Bibliográficos
Autores principales: DiGiandomenico, Antonio, Warrener, Paul, Hamilton, Melissa, Guillard, Sandrine, Ravn, Peter, Minter, Ralph, Camara, Maria Margarita, Venkatraman, Vignesh, MacGill, Randall S., Lin, Jia, Wang, Qun, Keller, Ashley Elaine, Bonnell, Jessica C., Tomich, Mladen, Jermutus, Lutz, McCarthy, Michael P., Melnick, David A., Suzich, JoAnn A., Stover, C. Kendall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405507/
https://www.ncbi.nlm.nih.gov/pubmed/22734046
http://dx.doi.org/10.1084/jem.20120033

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