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Direct reprogramming of human astrocytes into neural stem cells and neurons

Generating neural stem cells and neurons from reprogrammed human astrocytes is a potential strategy for neurological repair. Here we show dedifferentiation of human cortical astrocytes into the neural stem/progenitor phenotype to obtain progenitor and mature cells with a neural fate. Ectopic express...

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Detalles Bibliográficos
Autores principales: Corti, Stefania, Nizzardo, Monica, Simone, Chiara, Falcone, Marianna, Donadoni, Chiara, Salani, Sabrina, Rizzo, Federica, Nardini, Martina, Riboldi, Giulietta, Magri, Francesca, Zanetta, Chiara, Faravelli, Irene, Bresolin, Nereo, Comi, Giacomo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405531/
https://www.ncbi.nlm.nih.gov/pubmed/22426197
http://dx.doi.org/10.1016/j.yexcr.2012.02.040