Adult-Onset Fluoxetine Treatment Does Not Improve Behavioral Impairments and May Have Adverse Effects on the Ts65Dn Mouse Model of Down Syndrome

Down syndrome is caused by triplication of chromosome 21 and is associated with neurocognitive phenotypes ranging from severe intellectual disability to various patterns of more selective neuropsychological deficits, including memory impairments. In the Ts65Dn mouse model of Down syndrome, excessive...

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Detalles Bibliográficos
Autores principales: Heinen, Markus, Hettich, Moritz M., Ryan, Devon P., Schnell, Susanne, Paesler, Katharina, Ehninger, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405721/
https://www.ncbi.nlm.nih.gov/pubmed/22848851
http://dx.doi.org/10.1155/2012/467251

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