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The Yeast Rab GTPase Ypt1 Modulates Unfolded Protein Response Dynamics by Regulating the Stability of HAC1 RNA

The unfolded protein response (UPR) is a conserved mechanism that mitigates accumulation of unfolded proteins in the ER. The yeast UPR is subject to intricate post-transcriptional regulation, involving recruitment of the RNA encoding the Hac1 transcription factor to the ER and its unconventional spl...

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Detalles Bibliográficos
Autores principales: Tsvetanova, Nikoleta G., Riordan, Daniel P., Brown, Patrick O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406009/
https://www.ncbi.nlm.nih.gov/pubmed/22844259
http://dx.doi.org/10.1371/journal.pgen.1002862