Intact p53-Dependent Responses in miR-34–Deficient Mice

MicroRNAs belonging to the miR-34 family have been proposed as critical modulators of the p53 pathway and potential tumor suppressors in human cancers. To formally test these hypotheses, we have generated mice carrying targeted deletion of all three members of this microRNA family. We show that comp...

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Detalles Bibliográficos
Autores principales: Concepcion, Carla P., Han, Yoon-Chi, Mu, Ping, Bonetti, Ciro, Yao, Evelyn, D'Andrea, Aleco, Vidigal, Joana A., Maughan, William P., Ogrodowski, Paul, Ventura, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406012/
https://www.ncbi.nlm.nih.gov/pubmed/22844244
http://dx.doi.org/10.1371/journal.pgen.1002797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406012/
https://www.ncbi.nlm.nih.gov/pubmed/22844244
http://dx.doi.org/10.1371/journal.pgen.1002797

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