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Rapid Turnover of Long Noncoding RNAs and the Evolution of Gene Expression

A large proportion of functional sequence within mammalian genomes falls outside protein-coding exons and can be transcribed into long RNAs. However, the roles in mammalian biology of long noncoding RNA (lncRNA) are not well understood. Few lncRNAs have experimentally determined roles, with some of...

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Detalles Bibliográficos
Autores principales: Kutter, Claudia, Watt, Stephen, Stefflova, Klara, Wilson, Michael D., Goncalves, Angela, Ponting, Chris P., Odom, Duncan T., Marques, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406015/
https://www.ncbi.nlm.nih.gov/pubmed/22844254
http://dx.doi.org/10.1371/journal.pgen.1002841