Pre-Targeting and Direct Immunotargeting of Liposomal Drug Carriers to Ovarian Carcinoma

BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors. However, the ratio of tumor-to-normal tissue concentrations should be increased t...

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Detalles Bibliográficos
Autores principales: Lehtinen, Julia, Raki, Mari, Bergström, Kim A., Uutela, Päivi, Lehtinen, Katariina, Hiltunen, Annukka, Pikkarainen, Jere, Liang, Huamin, Pitkänen, Sari, Määttä, Ann-Marie, Ketola, Raimo A., Yliperttula, Marjo, Wirth, Thomas, Urtti, Arto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406029/
https://www.ncbi.nlm.nih.gov/pubmed/22844475
http://dx.doi.org/10.1371/journal.pone.0041410

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