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NEMO Inhibits Programmed Necrosis in an NFκB-Independent Manner by Restraining RIP1

TNF can trigger two opposing responses: cell survival and cell death. TNFR1 activates caspases that orchestrate apoptosis but some cell types switch to a necrotic death when treated with caspase inhibitors. Several genes that are required to orchestrate cell death by programmed necrosis have been id...

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Detalles Bibliográficos
Autores principales:	O’Donnell, Marie Anne, Hase, Hidenori, Legarda, Diana, Ting, Adrian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406058/ https://www.ncbi.nlm.nih.gov/pubmed/22848449 http://dx.doi.org/10.1371/journal.pone.0041238

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