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Retinal Ganglion Cell Loss Is Accompanied by Antibody Depositions and Increased Levels of Microglia after Immunization with Retinal Antigens

BACKGROUND: Antibodies against retinal and optic nerve antigens are detectable in glaucoma patients. Recent studies using a model of experimental autoimmune glaucoma demonstrated that immunization with certain ocular antigens causes an immun-mediated retinal ganglion cell loss in rats. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales:	Joachim, Stephanie C., Gramlich, Oliver W., Laspas, Panagiotis, Schmid, Heiko, Beck, Sabine, von Pein, Harald D., Dick, H. Burkhard, Pfeiffer, Norbert, Grus, Franz H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406064/ https://www.ncbi.nlm.nih.gov/pubmed/22848388 http://dx.doi.org/10.1371/journal.pone.0040616

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