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Activation and Proteolytic Activity of the Treponema pallidum Metalloprotease, Pallilysin

Treponema pallidum is a highly invasive pathogen that undergoes rapid dissemination to establish widespread infection. Previous investigations identified the T. pallidum adhesin, pallilysin, as an HEXXH-containing metalloprotease that undergoes autocatalytic cleavage and degrades laminin and fibrino...

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Detalles Bibliográficos
Autores principales: Houston, Simon, Hof, Rebecca, Honeyman, Lisa, Hassler, Julia, Cameron, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406077/
https://www.ncbi.nlm.nih.gov/pubmed/22910436
http://dx.doi.org/10.1371/journal.ppat.1002822