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Activation and Proteolytic Activity of the Treponema pallidum Metalloprotease, Pallilysin
Treponema pallidum is a highly invasive pathogen that undergoes rapid dissemination to establish widespread infection. Previous investigations identified the T. pallidum adhesin, pallilysin, as an HEXXH-containing metalloprotease that undergoes autocatalytic cleavage and degrades laminin and fibrino...
Autores principales: | Houston, Simon, Hof, Rebecca, Honeyman, Lisa, Hassler, Julia, Cameron, Caroline E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406077/ https://www.ncbi.nlm.nih.gov/pubmed/22910436 http://dx.doi.org/10.1371/journal.ppat.1002822 |
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