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Opposing Roles for Interferon Regulatory Factor-3 (IRF-3) and Type I Interferon Signaling during Plague

Type I interferons (IFN-I) broadly control innate immunity and are typically transcriptionally induced by Interferon Regulatory Factors (IRFs) following stimulation of pattern recognition receptors within the cytosol of host cells. For bacterial infection, IFN-I signaling can result in widely varian...

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Detalles Bibliográficos
Autores principales:	Patel, Ami A., Lee-Lewis, Hanni, Hughes-Hanks, Jennifer, Lewis, Craig A., Anderson, Deborah M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406097/ https://www.ncbi.nlm.nih.gov/pubmed/22911267 http://dx.doi.org/10.1371/journal.ppat.1002817

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