Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications

The ECG is a rapidly available clinical tool that can help clinicians manage poisoned patients. Specific myocardial effects of cardiotoxic drugs have well-described electrocardiographic manifestations. In the practice of clinical toxicology, classic ECG changes may hint at blockade of ion channels,...

Descripción completa

Detalles Bibliográficos
Autores principales: Yates, Christopher, Manini, Alex F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406273/
https://www.ncbi.nlm.nih.gov/pubmed/22708912
http://dx.doi.org/10.2174/157340312801784961
_version_ 1782239213274529792
author Yates, Christopher
Manini, Alex F
author_facet Yates, Christopher
Manini, Alex F
author_sort Yates, Christopher
collection PubMed
description The ECG is a rapidly available clinical tool that can help clinicians manage poisoned patients. Specific myocardial effects of cardiotoxic drugs have well-described electrocardiographic manifestations. In the practice of clinical toxicology, classic ECG changes may hint at blockade of ion channels, alterations of adrenergic tone, or dysfunctional metabolic activity of the myocardium. This review will offer a structured approach to ECG interpretation in poisoned patients with a focus on clinical implications and ECG-based management recommendations in the initial evaluation of patients with acute cardiotoxicity.
format Online
Article
Text
id pubmed-3406273
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Bentham Science Publishers
record_format MEDLINE/PubMed
spelling pubmed-34062732013-05-01 Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications Yates, Christopher Manini, Alex F Curr Cardiol Rev Article The ECG is a rapidly available clinical tool that can help clinicians manage poisoned patients. Specific myocardial effects of cardiotoxic drugs have well-described electrocardiographic manifestations. In the practice of clinical toxicology, classic ECG changes may hint at blockade of ion channels, alterations of adrenergic tone, or dysfunctional metabolic activity of the myocardium. This review will offer a structured approach to ECG interpretation in poisoned patients with a focus on clinical implications and ECG-based management recommendations in the initial evaluation of patients with acute cardiotoxicity. Bentham Science Publishers 2012-05 2012-05 /pmc/articles/PMC3406273/ /pubmed/22708912 http://dx.doi.org/10.2174/157340312801784961 Text en © 2012 Bentham Science Publishers https://creativecommons.org/licenses/by/2.5/This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Yates, Christopher
Manini, Alex F
Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications
title Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications
title_full Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications
title_fullStr Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications
title_full_unstemmed Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications
title_short Utility of the Electrocardiogram in Drug Overdose and Poisoning: Theoretical Considerations and Clinical Implications
title_sort utility of the electrocardiogram in drug overdose and poisoning: theoretical considerations and clinical implications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406273/
https://www.ncbi.nlm.nih.gov/pubmed/22708912
http://dx.doi.org/10.2174/157340312801784961
work_keys_str_mv AT yateschristopher utilityoftheelectrocardiogramindrugoverdoseandpoisoningtheoreticalconsiderationsandclinicalimplications
AT maninialexf utilityoftheelectrocardiogramindrugoverdoseandpoisoningtheoreticalconsiderationsandclinicalimplications

Ejemplares similares