Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro

Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain their undifferentiated state. In this study, we found significant growth inhibition of mouse ESCs (mESCs) cultured on...

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Detalles Bibliográficos
Autores principales: Kim, Gu-Hee, Lee, Gong-Rak, Choi, Hyung-Im, Park, Neung-Hwa, Chung, Hun Taeg, Han, In-Seob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406291/
https://www.ncbi.nlm.nih.gov/pubmed/22595769
http://dx.doi.org/10.3858/emm.2012.44.7.052

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