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Genomic evolution in Barrett’s adenocarcinoma cells: critical roles of elevated hsRAD51, homologous recombination and Alu sequences in the genome

A prominent feature of most cancers including Barrett’s adenocarcinoma (BAC) is genetic instability, which is associated with development and progression of disease. In this study, we investigated the role of recombinase (hsRAD51), a key component of homologous recombination (HR)/repair, in evolving...

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Detalles Bibliográficos
Autores principales: Pal, J, Bertheau, R, Buon, L, Qazi, A, Batchu, RB, Bandyopadhyay, S, Ali-Fehmi, R, Beer, DG, Weaver, DW, Reis, RJ Shmookler, Goyal, RK, Huang, Q, Munshi, NC, Shammas, MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406293/
https://www.ncbi.nlm.nih.gov/pubmed/21423218
http://dx.doi.org/10.1038/onc.2011.83