Three to Tango: MUC1 as a Ligand for Both E-Selectin and ICAM-1 in the Breast Cancer Metastatic Cascade

Cancer cell tethering and rolling on the vascular wall is facilitated by various selectin: glycoprotein interactions which lead to eventual extravasation and metastases. The aberrantly underglycosylated mucin MUC1 has been shown to both abundantly express selectin binding moieties (sialyl Lewis x an...

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Detalles Bibliográficos
Autores principales: Geng, Yue, Yeh, Kimberly, Takatani, Tait, King, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406322/
https://www.ncbi.nlm.nih.gov/pubmed/22866263
http://dx.doi.org/10.3389/fonc.2012.00076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406322/
https://www.ncbi.nlm.nih.gov/pubmed/22866263
http://dx.doi.org/10.3389/fonc.2012.00076

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